Nucleic-acid-loaded particles approaching skeletal muscle fibres
Research & development

Developing new
therapeutic concepts

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preclinics discovery

preclinics discovery is a subsidiary of preclinics GmbH. As a contract research and development organisation (CRDO), we take on development projects for our clients and develop our own technology platforms, which partners can use and license. Our work is supported by the preclinical and bioanalytical expertise of preclinics.

Therapeutic R&DNucleic acid deliveryNeedle-free administrationImmunisation platformsLicensing & partnerships
Projects

Ongoing projects

Nerve terminals contacting a muscle fibre at the neuromuscular junction
BoNTANA

Botulinum neurotoxin, delivered as a nucleic acid

BoNT encoded as mRNA or DNA, aiming for a longer-lasting effect and an improved safety profile.

Neuromuscular junctionmRNA / DNA
Particles carrying nucleic acids released from a depot
NaPure

Depot formulations for mRNA transfection

Formulations designed to extend mRNA expression while lowering toxicity.

Depot formulationmRNA
Needle-free injector releasing fine droplets into skin tissue
Needle-free microinjection

Gentle treatment of larger skin areas

Needle-free microinjection for pain-free treatment of larger skin areas.

Needle-freeDermal delivery
Antibodies binding antigens
VacciTag™

Strong antibody responses to difficult antigens

VacciTag™ uses pre-existing tetanus immunity to generate high antibody titers without harsh, toxic adjuvants.

ImmunisationAntibody titers

Interested in a platform or a development project?

Talk to us about licensing one of our platforms or developing your own therapeutic concept. We will discuss feasibility, study design and next steps with you.

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